Overview
Gregg L. Semenza is a hypoxia signaling specialist with an H-index of 194 at Johns Hopkins University (Faculty). Has been published in Nature reviews. Cancer, Proceedings of the National Academy of Sciences, Molecular and Cellular Biology. Based in United States.
Biography
Gregg Leonard Semenza is an American pediatrician and Professor of Genetic Medicine at the Johns Hopkins School of Medicine. He serves as the director of the vascular program at the Institute for Cell Engineering. He is a 2016 recipient of the Albert Lasker Award for Basic Medical Research. He is known for his discovery of HIF-1, which allows cancer cells to adapt to oxygen-poor environments. He shared the 2019 Nobel Prize in Physiology or Medicine for "discoveries of how cells sense and adapt to oxygen availability" with William Kaelin Jr. and Peter J. Ratcliffe. Semenza has had thirteen research papers retracted due to issues such as duplicated images and potential data manipulation.
Affiliations & Institutions
Research Impact
5 Publications
0 Total Citations
Publication Timeline
Published In
CellAutophagyJ Clin InvestAdv Exp Med BiolNat Rev Cancer
Key Publications
Hypoxia-inducible factors in physiology and medicine.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Hypoxia-inducible factors: cancer progression and clinical translation.
Master Role of Hypoxia in Cancer Progression: Major Insights During ISOTT's Half-Century.
Targeting HIF-1 for cancer therapy.
Areas of Expertise
Medical Specialties
Media Archive