Ruth Nussenzweig
Parasitology · Malaria Immunology
New York, Brazil
Overview
Ruth Nussenzweig was a parasitology and immunology specialist with an H-index of 70 at NYU School of Medicine. Pioneer of malaria vaccine research whose work led to the RTS,S vaccine. Based in New York, United States.
For Patients
- Pioneered the Irradiated sporozoite malaria vaccination approach, a technique still used by doctors worldwide
- Research was cited 6K+ times by other doctors and scientists
- Based at New York University School of Medicine in New York, Brazil
Biography
Affiliations & Institutions
Research Impact
Publication Timeline
Published In
Key Publications
Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei
γ Interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites
TRAP Is Necessary for Gliding Motility and Infectivity of Plasmodium Sporozoites
Migration of <i>Plasmodium</i> Sporozoites Through Cells Before Infection
Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria
Areas of Expertise
Pioneering Techniques
Medical Specialties
Clinical Knowledge & Procedures
Legacy Timeline
The life and contributions of Ruth Nussenzweig
Demonstrated irradiated sporozoites protect against malaria
Published landmark paper showing immunization with irradiated sporozoites prevents malaria infection
Identified circumsporozoite protein
Discovered the major surface protein of Plasmodium sporozoites
Cloned circumsporozoite protein gene
Enabled molecular development of subunit malaria vaccines
RTS,S vaccine approved by WHO
The Mosquirix malaria vaccine, built on her foundational work, received WHO recommendation