Overview
Tasuku Honjo is a pd-1 immunotherapy specialist with an H-index of 175 at Kyoto University (Faculty). Has been published in Cell, Proceedings of the National Academy of Sciences, Nature Immunology. Based in Japan.
Biography
Tasuku Honjo is a Japanese physician-scientist and immunologist. He won the 2018 Nobel Prize in Physiology or Medicine and is best known for his identification of programmed cell death protein 1 (PD-1). He is also known for his molecular identification of cytokines IL-4 and IL-5, as well as the discovery of activation-induced cytidine deaminase (AID) that is essential for class switch recombination and somatic hypermutation.
Affiliations & Institutions
Research Impact
5 Publications
0 Total Citations
Publication Timeline
Published In
ScienceNatureSci ImmunolTrends Cell BiolImmunity
Key Publications
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice.
B cell-derived GABA elicits IL-10(+) macrophages to limit anti-tumour immunity.
Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases.
Spermidine - an old molecule with a new age-defying immune function.
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling.
Areas of Expertise
Medical Specialties
Clinical Knowledge & Procedures
Media Archive